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WDR20 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - WDR20 Antibody (N-term) AP17832a
    WDR20 Antibody (N-term) (Cat. #AP17832a) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the WDR20 antibody detected the WDR20 protein (arrow).
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8TBZ3
Other Accession NP_653175.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 62893 Da
Antigen Region 5-32 aa
Additional Information
Gene ID 91833
Other Names WD repeat-containing protein 20, Protein DMR, WDR20
Target/Specificity This WDR20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-32 amino acids from the N-terminal region of human WDR20.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsWDR20 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDR20
Function Regulator of deubiquitinating complexes. Activates deubiquitinating activity of complexes containing USP12 (PubMed:20147737, PubMed:27373336). Anchors at the base of the ubiquitin-contacting loop of USP12 and remotely modulates the catalytic center of the enzyme (PubMed:27373336). Regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus (PubMed:30466959).
Cellular Location Cytoplasm. Nucleus
Citations (0)
citation

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Background

This gene encodes a WD repeat-containing protein. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kee, Y., et al. J. Biol. Chem. 285(15):11252-11257(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 365.00
$ 140.00
Cat# AP17832a
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