ANKS4B Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q8N8V4 |
Other Accession | NP_665872.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 46597 Da |
Antigen Region | 184-213 aa |
Gene ID | 257629 |
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Other Names | Ankyrin repeat and SAM domain-containing protein 4B, Harmonin-interacting ankyrin repeat-containing protein, Harp, ANKS4B, HARP |
Target/Specificity | This ANKS4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-213 amino acids from the Central region of human ANKS4B. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ANKS4B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ANKS4B (HGNC:26795) |
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Function | As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. Plays a role in assembly of the complex (PubMed:26812018). May play a role in cellular response to endoplasmic reticulum stress (By similarity). |
Cellular Location | Cell projection, microvillus Note=Localizes at the tip of microvilli (PubMed:26812018, PubMed:32209652). May associate with endoplasmic reticulum membranes (By similarity). {ECO:0000250|UniProtKB:Q8K3X6, ECO:0000269|PubMed:26812018, ECO:0000269|PubMed:32209652} |
Tissue Location | Expressed in kidney and small intestine. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Johnston, A.M., et al. Genes Cells 9(10):967-982(2004)
Weil, D., et al. Hum. Mol. Genet. 12(5):463-471(2003)
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