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(DANRE) cyfip1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q90YM8 |
| Reactivity | Zebrafish |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Clone/Animal Names | RB47040 |
| Calculated MW | 145174 Da |
| Antigen Region | 524-558 aa |
| Gene ID | 336613 |
|---|---|
| Other Names | Cytoplasmic FMR1-interacting protein 1 homolog, cyfip1 {ECO:0000312|ZFIN:ZDB-GENE-030131-8557} |
| Target/Specificity | This DANRE cyfip1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 524-558 amino acids from the Central region of DANRE cyfip1. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | (DANRE) cyfip1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | cyfip1 {ECO:0000312|ZFIN:ZDB-GENE-030131-8557} |
|---|---|
| Function | Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q7TMB8}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q7TMB8}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:Q7TMB8}. Cell projection, ruffle {ECO:0000250|UniProtKB:Q7TMB8}. Synapse, synaptosome {ECO:0000250|UniProtKB:Q7TMB8}. Note=Highly expressed in the perinuclear region (By similarity). Enriched in synaptosomes (By similarity). Also enriched in membrane ruffles and at the tips of lamellipodia (By similarity). {ECO:0000250|UniProtKB:Q7TMB8} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA (By similarity).
References
Schenck A.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:8844-8849(2001).
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