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SNCB Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SNCB Antibody (C-term) AP5842B
    Anti-SNCB Antibody (C-term) at 1:1000 dilution + human brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 14 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • WB - SNCB Antibody (C-term) AP5842B
    SNCB Antibody (C-term) (Cat. #AP5842b) western blot analysis in mouse cerebellum tissue lysates (15ug/lane).This demonstrates the SNCB antibody detected SNCB protein (arrow).
    detail
  • IHC-P - SNCB Antibody (C-term) AP5842B
    SNCB antibody(C-term) (Cat. #AP5842b) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SNCB antibody(C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q16143
Other Accession NP_001001502.1, NP_003076.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 14288 Da
Antigen Region 93-122 aa
Additional Information
Gene ID 6620
Other Names Beta-synuclein, SNCB
Target/Specificity This SNCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the C-terminal region of human SNCB.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNCB Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNCB
Function Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Cellular Location Cytoplasm.
Tissue Location Expressed predominantly in brain; concentrated in presynaptic nerve terminals
Research Areas
Citations (0)
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$ 365.00
$ 140.00
Cat# AP5842B
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