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Anti-AAAS / Adracalin Antibody (clone 5A1)

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9NRG9
Predicted Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG2a,k
Clone Names 5A1
Calculated MW 59574 Da
Dilution ELISA, IHC-P (5 µg/ml), WB (1:500 - 1:1000)
Additional Information
Gene ID 8086
Alias Symbol AAAS
Other Names AAAS, Aladin, AAASb, ADRACALA, Allgrove, triple-A, AAA, ADRACALIN, GL003
Target/Specificity Human AAAS
Reconstitution & Storage Protein A purified
PrecautionsAnti-AAAS / Adracalin Antibody (clone 5A1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AAAS
Synonyms ADRACALA
Function Plays a role in the normal development of the peripheral and central nervous system (PubMed:11062474, PubMed:11159947, PubMed:16022285). Required for the correct localization of aurora kinase AURKA and the microtubule minus end-binding protein NUMA1 as well as a subset of AURKA targets which ensures proper spindle formation and timely chromosome alignment (PubMed:26246606).
Cellular Location Nucleus, nuclear pore complex. Cytoplasm, cytoskeleton, spindle pole. Nucleus envelope. Note=In metaphase cells localizes within the spindle with some accumulation around spindle poles, with the highest concentration between the centrosome and metaphase plate (PubMed:26246606). The localization to the spindle is microtubule- mediated (PubMed:26246606).
Tissue Location Widely expressed (PubMed:11159947, PubMed:16022285). Particularly abundant in cerebellum, corpus callosum, adrenal gland, pituitary gland, gastrointestinal structures and fetal lung (PubMed:11159947).
Research Areas
Citations (0)
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Discontinued
Cat# ALS17698
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