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ADRB2 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - ADRB2 Antibody (C-Terminus) ALS10563
    Anti-ADRB2 antibody ALS10563 IHC of human heart, cardiac myocytes.
    detail
  • IHC - ADRB2 Antibody (C-Terminus) ALS10563
    Anti-ADRB2 antibody IHC of human Brain, Glioblastoma.
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  • IHC - ADRB2 Antibody (C-Terminus) ALS10563
    Anti-ADRB2 antibody IHC of human Colon, Carcinoma.
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  • IHC - ADRB2 Antibody (C-Terminus) ALS10563
    Anti-ADRB2 antibody IHC of human Prostate, Carcinoma.
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  • ICC - ADRB2 Antibody (C-Terminus) ALS10563
    Anti-ADRB2 antibody ALS10563 immunocytochemistry (ICC) staining of HEK293 human embryonic kidney...
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  • ICC - ADRB2 Antibody (C-Terminus) ALS10563
    Anti-ADRB2 antibody ALS10563 immunocytochemistry (ICC) staining of untransfected HEK293 human...
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  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession P07550
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 46kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 154
Other Names Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2, ADRB2R, B2AR
Target/Specificity Human ADRB2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsADRB2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADRB2
Synonyms ADRB2R, B2AR
Function Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine.
Cellular Location Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus. Note=Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325) Activated receptors are also detected within the Golgi apparatus (PubMed:27481942).
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

References

Chung F.-Z.,et al.FEBS Lett. 211:200-206(1987).
Kobilka B.K.,et al.J. Biol. Chem. 262:7321-7327(1987).
Schofield P.R.,et al.Nucleic Acids Res. 15:3636-3636(1987).
Kobilka B.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:46-50(1987).
Emorine L.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:6995-6999(1987).

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$ 467.50
Cat# ALS10563
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